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How do the IL-5 inhibitors Cinqair, Fasenra, and Nucala work?

The IL-5 inhibitors Cinqair (reslizumab), Fasenra (benralizumab), and Nucala (mepolizumab) block IL-5 and help control eosinophils.  How do they work and what are the differences between them? Why target IL-5? IL-5 is a cytokine, a small signaling molecule.  IL-5 is produced and secreted by T cells and mast cells.  The IL-5 molecules can then signal to […]

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